 | Buffalo Sabres2021-2022 Schedule |
| Date | Time | Opponent |
|---|---|---|
| Regular Season | ||
| Thu, Oct 14 | 6:00 PM | vs  Montreal Canadiens |
| Sat, Oct 16 | 12:00 PM | vs  Arizona Coyotes |
| Tue, Oct 19 | 6:00 PM | vs  Vancouver Canucks |
| Fri, Oct 22 | 6:00 PM | vs  Boston Bruins |
| Sat, Oct 23 | 6:00 PM | @  New Jersey Devils |
| Mon, Oct 25 | 6:00 PM | vs  Tampa Bay Lightning |
| Thu, Oct 28 | 9:00 PM | @  Anaheim Ducks |
| Sun, Oct 31 | 3:00 PM | @  Los Angeles Kings |