All times ET| Date | Time | Opponent |
|---|
| Tue, May 1 | 7:00 PM | @ Cleveland Indians |
| Wed, May 2 | 7:00 PM | @ Cleveland Indians |
| Thu, May 3 | 7:00 PM | vs Boston Red Sox |
| Fri, May 4 | 7:00 PM | vs Boston Red Sox |
| Sat, May 5 | 7:00 PM | vs Boston Red Sox |
| Sun, May 6 | 7:00 PM | vs Boston Red Sox |
| Mon, May 7 | 7:00 PM | vs Detroit Tigers |
| Tue, May 8 | 7:00 PM | vs Detroit Tigers |
| Wed, May 9 | 7:00 PM | vs Detroit Tigers |
| Fri, May 11 | 8:10 PM | @ Houston Astros |
| Sat, May 12 | 7:10 PM | @ Houston Astros |
| Sun, May 13 | 2:10 PM | @ Houston Astros |
| Tue, May 15 | 10:10 PM | @ Seattle Mariners |
| Wed, May 16 | 3:40 PM | @ Seattle Mariners |
| Thu, May 17 | 7:00 PM | @ Chicago White Sox |
| Fri, May 18 | 7:00 PM | @ Chicago White Sox |
| Sat, May 19 | 7:00 PM | @ Chicago White Sox |
| Sun, May 20 | 7:00 PM | @ Chicago White Sox |
| Mon, May 21 | 7:00 PM | vs New York Yankees |
| Tue, May 22 | 7:00 PM | vs New York Yankees |
| Wed, May 23 | 7:00 PM | vs New York Yankees |
| Thu, May 24 | 7:00 PM | vs Kansas City Royals |
| Fri, May 25 | 7:00 PM | vs Kansas City Royals |
| Sat, May 26 | 7:00 PM | vs Kansas City Royals |
| Sun, May 27 | 7:00 PM | vs Kansas City Royals |
| Mon, May 28 | 10:10 PM | @ Seattle Mariners |
| Tue, May 29 | 10:10 PM | @ Seattle Mariners |
| Wed, May 30 | 10:10 PM | @ Seattle Mariners |
| Thu, May 31 | 10:10 PM | @ Seattle Mariners |
