All times ET| Date | Time | Opponent |
|---|
| Tue, May 1 | 7:00 PM | vs Texas Rangers |
| Wed, May 2 | 7:00 PM | vs Texas Rangers |
| Fri, May 4 | 7:00 PM | @ New York Yankees |
| Sat, May 5 | 7:00 PM | @ New York Yankees |
| Sun, May 6 | 7:00 PM | @ New York Yankees |
| Tue, May 8 | 7:40 PM | @ Milwaukee Brewers |
| Wed, May 9 | 1:10 PM | @ Milwaukee Brewers |
| Fri, May 11 | 7:00 PM | vs Kansas City Royals |
| Sat, May 12 | 7:00 PM | vs Kansas City Royals |
| Sun, May 13 | 7:00 PM | vs Kansas City Royals |
| Mon, May 14 | 7:10 PM | @ Detroit Tigers |
| Tue, May 15 | 7:10 PM | @ Detroit Tigers |
| Wed, May 16 | 1:10 PM | @ Detroit Tigers |
| Fri, May 18 | 8:10 PM | @ Houston Astros |
| Sat, May 19 | 4:10 PM | @ Houston Astros |
| Sun, May 20 | 2:10 PM | @ Houston Astros |
| Tue, May 22 | 8:05 PM | @ Chicago Cubs |
| Wed, May 23 | 8:05 PM | @ Chicago Cubs |
| Thu, May 24 | 7:00 PM | vs Houston Astros |
| Fri, May 25 | 7:00 PM | vs Houston Astros |
| Sat, May 26 | 7:00 PM | vs Houston Astros |
| Sun, May 27 | 7:00 PM | vs Houston Astros |
| Mon, May 28 | 7:00 PM | vs Chicago White Sox |
| Tue, May 29 | 7:00 PM | vs Chicago White Sox |
| Wed, May 30 | 7:00 PM | vs Chicago White Sox |
| Thu, May 31 | 8:10 PM | @ Minnesota Twins |
